Mason (7-4, KenPom: 123) has now won five straight after a 2-4 start.
Victor Bailey Jr. led the Patriots with 19 points, shooting 5-of-9 from three-point range.
Tulane (6-4, KenPom: 94) was just 2-of-18 from three in the defeat.
Mason also got a nice all-around game from Josh Oduro, who stuffed the stat sheet with 12 points, six rebounds and two blocks, with nine of those points coming in the final six minutes of action.
With his seventh point of the contest, Oduro became the 40th player in program history to score 1,000 career points in a Mason uniform.
DeVon Cooper chipped in eight points and dished out a career-best seven assists, while junior Ronald Polite III added five assists in 31 minutes.
Polite also helpled hold Tulane leading scorer Jalen Cook (20.8 ppg) to just 11 points on 20 shots (4-of-20 FG).
George Mason now heads south within the Commonwealth to renew a historic rivalry with Old Dominion on Wednesday.
Tip-off between the Patriots and Monarchs is set for 4 p.m. The game will be broadcast on ESPN+.
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Chris Graham
