UVA discovery offers look at regulation of gene expression
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A groundbreaking new technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression – in single cells. The technique enables researchers, for the first time, to analyze the process within the individual cell types that make up complex tissues, overcoming a major limitation of traditional analysis and offering unprecedented opportunities for understanding mechanisms that contribute to development of major human diseases, including cancer, cardiovascular and neurological diseases.
