Duke at Northwestern, Noon, ESPNU, 135, 193, 955
Series: Northwestern leads, 10-9; Last meeting: Duke, 41-17 (2017)
ESPNU: Jason Benetti, Kelly Stouffer, Olivia Dekker
Line: Northwestern -2.5
Capsule: Duke looked good in its big win over Army. Northwestern has won nine straight.
Pick: Northwestern 30, Duke 24
Towson at Wake Forest, Noon, ACCNE, 138, 380, 966
Series: First Meeting
ACC Network Extra: Shawn Kenney, Stan Lewter
Line: Wake Forest -17.5
Capsule: Beware of Tom Flacco. Not really.
Pick: Wake Forest 28, Towson 10
Georgia Tech at USF, Noon, ABC/ESPN2, 119, 194, 956 Series: First Meeting
ABC/ESPN2: Adam Amin, Rod Gilmore, Quint Kessenich
Line: Georgia Tech -3.5
Capsule: Both teams played cupcakes last week.
Pick: Georgia Tech 23, South Florida 20
Georgia State at NC State, 12:30 p.m., RSN, 108, 381, 967 Series: First Meeting
RSN: Wes Durham, James Bates, Rebecca Kaple
Line: NC State -24.5
Capsule: NC State escaped JMU. This one should be easier.
Pick: NC State 35, Georgia State 14
Holy Cross at Boston College, 1 p.m., ACCNE, 205, 382, 968 Series: Boston College leads series, 48-31-3; Last meeting: Boston College, 56-26 (1986)
ACC Network Extra: Robert Lee, Matt Chatham
Line: Boston College -43
Capsule: Holy Cross lost to Colgate last week.
Pick: Boston College 62, Holy Cross 10
William & Mary at No. 12/14 Virginia Tech, 2 p.m., ACCNE, 78, 202, 974 Series: Virginia Tech leads series, 41-18-4; Last meeting: Virginia Tech, 34-9 (2014)
ACC Network Extra: Joel Meyers, Dustin Fox
Line: Virginia Tech -37.5
Capsule: William & Mary beat Bucknell 14-7 last week.
Pick: Virginia Tech 48, William & Mary 7
Wagner at Syracuse, 3:30 p.m., ACCNE, 119, 194, 956
Series: Syracuse leads series,1-0; Last meeting: SU, 54-0 (2013)
ACC Network Extra: Doug Sherman, Al Groh
Line: Syracuse -41.5
Capsule: Wagner beat Bowie State 40-23 last week.
Pick: Syracuse 48, Wagner 17
North Carolina at East Carolina, 3:30 p.m., ESPNU, 135, 193, 955 Series: UNC leads series, 12-4-1; Last meeting: ECU, 70-41 (2014)
ESPNU: Mike Corey, Rene Ingoglia
Line: North Carolina -16.5
Capsule: ECU lost to North Carolina A&T last week. Yeah, ugh.
Pick: North Carolina 38, East Carolina 12
Savannah State at No. 22/21 Miami, 6 p.m., ACCNE, 78, 202, 974
Series: Miami leads series, 1-0; Last meeting: Miami, 77-7 (2013)
ACC Network Extra: Drew Fellios, Forrest Conoly
Line: Miami -54
Capsule: Savannah State lost 52-0 to UAB in its opener.
Pick: Miami 63, Savannah State 0
Indiana State at Louisville, 7 p.m., ACCNE, 138, 391, 979 Series: Louisville leads 6-3-1; Last meeting: Louisville, 30-10 (2009)
ACC Network Extra: Jim Barbar, John Gregory
Line: Louisville -44.5
Capsule: This ain’t Larry Bird’s Indiana State.
Pick: Louisville 45, Indiana State 10
No. 2/2 Clemson at Texas A&M, 7 p.m., ESPN, 135, 193, 955 Series: Texas A&M leads series, 3-1; Last meeting: Clemson, 25-24 (2005)
ESPN: Rece Davis, Kirk Herbstreit, Maria Taylor
Line: Clemson -12
Capsule: We saw last week why Jimbo Fisher fled Tallahassee.
Pick: Clemson 52, Texas A&M 14
Samford at Florida State, 7:20 p.m., ACC Network, 119, 194, 956
Series: Florida State leads series, 2-0; Last meeting: Florida State, 59-6 (2010)
ACC Network: Tom Werme, Dave Archer, Lericia Harris
Line: Florida State -33
Capsule: Samford is ranked ninth in FCS. No slouches.
Pick: Florida State 34, Samford 17
Virginia at Indiana, 7:30 p.m., BTN, 146, 390, 980 Series: Virginia leads series, 2-1; Last meeting: Indiana, 34-17 (2017)
BTN: Lisa Byington, J Leman, Michelle McMahon
Line: Indiana -6
Capsule: I’m hyperventilating about my ‘Hoos.
Pick: Virginia 38, Indiana 24
No. 13/10 Penn State at Pitt, 8 p.m., ABC, 84, 392, 986
Series: Penn State leads series, 51-43-4; Last meeting: Penn State, 33-14 (2017)
ABC: Sean McDonough, Todd Blackledge, Holly Rowe
Line: Penn State -8.5
Capsule: Penn State escaped last week at home.
Pick: Pitt 31, Penn State 30
Deion Sanders said this week, in a viral video blasting UVA Football for trying to poach one of his players, that he would let Virginia “have one” and not say anything about it.
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