Virginia State Police were on scene of a fatal crash at 7 a.m. Friday on Interstate 64 eastbound at the 159.9 mile-marker in Louisa County.
Virginia State Police Trooper G. Robinson investigated the crash.
A 2003 Honda Accord was traveling east on I-64 when it ran off the road to the right overcorrected to the left back over to the right, running off the road and striking a tree.
The driver of the Honda, Christopher E. Lee, 49 of Earlysville, died at the scene; he was wearing a seatbelt.
Speed is being considered a factor in the crash.