ACC Football Week 3 | Weekend schedule kicks off on Thursday night

The 2025 ACC Football conference season kicks off in earnest on Thursday night, with NC State and Wake Forest facing off at 7:30 p.m. ET on ESPN.

ACC Network gets a dud of a game on Friday night with Colgate at Syracuse.

Then on Saturday, it’s another day starting at noon ET and ending in the wee hours of Sunday morning.

Thursday, Sept. 11

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NC State at Wake Forest | 7:30 p.m. | ESPN

Series: NC State leads series, 69-43-6
Last meeting: Wake Forest, 34-30 (2024)
Line: NC State -7.5
Over/under: 51.5
Projected final score: NC State 28, Wake Forest 21

Friday, Sept. 12

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Colgate at Syracuse | 7 p.m. | ACCN

Series: Syracuse leads series, 32-31-5
Last meeting: Syracuse, 65-0 (2023)
Line: no line

Saturday, Sept. 13

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#12 Clemson at Georgia Tech | noon | ESPN

Series: Georgia Tech leads series, 50-36-2
Last meeting: Clemson, 42-21 (2023)
Line: Clemson -3.5
Over/under: 53.5
Projected final score: Clemson 28, Georgia Tech 24

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William & Mary at Virginia | noon | ACCN

Series: Virginia leads series, 32-6-1
Last meeting: Virginia, 27-13 (2023)
Line: no line

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Pitt at West Virginia | 3:30 p.m. | ESPN

Series: Pitt leads series, 63-41-3
Last meeting: Pitt, 38-34 (2024)
Line: Pitt -7
Over/under: 57.5
Projected final score: Pitt 33, West Virginia 24

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Richmond at North Carolina | 3:30 p.m. | ACCN

Series: North Carolina leads series, 12-2-0
Last meeting: Richmond, 27-18 (1978)
Line: no line

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SMU at Missouri State | 3:30 p.m. | ACCN

Series: First Meeting
Line: SMU -27.5
Over/under: 60.5
Projected final score: SMU 44, Missouri State 16

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#18 South Florida at #5 Miami | 4:30 p.m. | The CW

Series: Miami leads series, 6-1-0
Last meeting: Miami, 50-15 (2024)
Line: Miami -17.5
Over/under: 56.5
Projected final score: Miami 37, South Florida 20

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Old Dominion at Virginia Tech | 7 p.m. | ACCN

Series: Virginia Tech leads series, 4-2-0
Last meeting: Virginia Tech, 37-17 (2024)
Line: Virginia Tech -7.5
Over/under: 50.5
Projected final score: Virginia Tech 28, ODU 21

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Duke at Tulane | 8 p.m. | ESPN2

Series: Duke leads series, 3-2-0
Last meeting: Duke, 37-7 (2015)
Line: Duke -1.5
Over/under: 54.5
Projected final score: Duke 28, Tulane 27

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Minnesota at Cal | 10:30 p.m. | ESPN

Series: Cal leads series, 4-2-0
Last meeting: Cal, 35-21 (2009)
Line: Minnesota -1.5
Over/under: 43.5
Projected final score: Minnesota 22, Cal 21

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Boston College at Stanford | 10:30 p.m. | ACCN

Series: Series tied, 2-2-0
Last meeting: Boston College, 34-27 (2002)
Line: Boston College -12.5
Over/under: 44.5
Projected final score: Boston College 28, Stanford 17